Prostate cancer cells thrive on stress | Science Codex

Prostate cancer patients have increased levels of stress and anxiety; however, several recent studies have found that men who take drugs that interfere with the stress hormone adrenaline have a lower incidence of prostate cancer. In this issue of the Journal of Clinical Investigation George Kulik and colleagues at Wake Forest University examined the relationship between stress and cancer progression in a mouse model of prostate cancer. Kulik and colleagues found that mice that had been subjected to stress (exposed to the scent of a predator) exhibited a significantly reduced response to a drug that induces cancer cell death compared to their unstressed counterparts. Administration of adrenaline also blocked cancer cell death. Conversely, drugs that inhibited adrenaline signaling ablated the effect of stress on prostate cancer. These findings suggest that beta-blockers, which are used for the treatment of high blood pressure and block the effects of adrenaline, could increase the efficacy of anti-cancer therapies. In a companion commentary, Anil Sood and colleagues at MD Anderson Cancer Center discuss additional studies that will be required to move these findings from bench to bedside.

Source: http://www.sciencecodex.com/prostate_cancer_cells_thrive_on_stress-105723

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Petrol bombs fly again as Northern Irish flag protests continue

BELFAST (Reuters) - Northern Irish police were pelted by petrol bombs for the first time in almost two weeks on Friday after more protests at the removal of the British flag from Belfast City Hall.

Masked youths clashed with police on the streets of east Belfast on an almost nightly basis for six weeks after local councillors voted to end a century-old tradition of flying the flag, enraging some pro-British loyalists.

The worst violence had calmed in recent days and most demonstrations on Friday passed off without major incident. But later in the evening, some people hurled stones, bottles and petrol bombs at police. There were no arrests or injuries, a police spokesman said.

The violence has been the most sustained in the British-ruled province since a 1998 peace deal ended 30 years of conflict between Catholic Irish nationalists seeking union with Ireland and Protestant loyalists determined to remain part of the United Kingdom.

(Writing by Padraic Halpin in Dublin; Editing by Robin Pomeroy)

Source: http://news.yahoo.com/petrol-bombs-fly-again-northern-irish-flag-protests-235553391.html

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UK court identifies Barclays staff named in rate probe

LONDON (Reuters) - A number of Barclays current and past executives are on a shortlist of individuals named in regulatory documents referring to the bank's attempted rigging of global benchmark interest rates, court documents released on Friday showed.

The list includes the head of Barclays' investment bank, Rich Ricci, who has led a reputation-based review of all of Barclays' investment banking activities following the scandal, which saw the bank fined $453 million by United States and British authorities.

The list also includes finance director Chris Lucas, former Chief Executive Bob Diamond, former chief operating officer Jerry del Missier, and former compliance head Stephen Morse.

A British judge ordered the bank to reveal their identities during a preliminary hearing for a test case on the mis-selling of interest rate swaps brought by a residential care home operator.

A longer list of 104 individuals who were named in court papers was released on Thursday after the judge denied their request for anonymity. The shorter list of 25, released on Friday, names those specifically referred to in regulatory documents referring to Libor manipulation.

Twenty-four of the 25 had requested anonymity - the exception being former Barclays trader Jay Merchant, who went on to become head of swaps trading at UBS before leaving his position last August amid federal scrutiny of his activities while at Barclays.

None of those named is necessarily implicated in any wrongdoing.

Guardian Care Homes alleges Barclays mis-sold interest rate hedging products based on Libor (London interbank offered rate) in a case that is shining a light on those involved in the bank's interest rate-setting process.

(Editing by David Cowell)

Source: http://news.yahoo.com/uk-court-identifies-barclays-staff-named-rate-probe-133925057--sector.html

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Twelve South introduces the PlugBug World

Last year, I reviewed the PlugBug from Twelve South. ?It is a 10W USB charger that can be used alone or as a replacement for the power prongs on a MacBook power brick. ?When I purchased mine last year, the PlugBug was only available with US-style power prongs. ?The new PlugBug World still offers a [...]

Source: http://the-gadgeteer.com/2013/01/24/twelve-south-introduces-the-plugbug-world/

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Texas teachers, foundations converge on Capitol

AUSTIN, Texas (AP) -- Hundreds of teachers gathered at the state Capitol on Thursday to urge Texas lawmakers to roll back $5.4 billion in public education cuts imposed two years ago, while nearby a coalition of foundations pushed for reforms without necessarily spending more money.

Members of the Texas Classroom Teachers Association fanned out for a lobbying full-court press, meeting with state senators and representatives for their home districts and explaining how the funding loss has prompted layoffs and wage freezes, larger class sizes and pre-kindergarten cuts. Some teachers said janitorial staff cutbacks have forced them to take out their own classroom garbage, while others complained the loss of aides and librarians has them trying to be two places at once.

"We need to stop putting Band-Aids on things and pretending like that's enough," said Janie Baszile, a teacher for 34 years in the Galena Park Independent School District in greater Houston. She led a small group from the area on a trek to see nine lawmakers.

The Texas Legislature, facing a $27 billion budget deficit prompted by a sluggish economy in 2011, voted to slash $5.4 billion from public schools and educational grant programs. The state's economic outlook is brighter now, but budget drafts in both the House and Senate for 2014-15 failed to restore the cuts.

One of the offices Baszile's group visited was that of Rep. Craig Eiland, a Texas City Democrat who was not in. Instead, staff member Ann Drescher listened to the group talk about deemphasizing high-stakes standardized testing and improving state classroom discipline mechanisms.

"Is there any talk about funding?" teacher Ruby Tanguma, finally asked. "That really hurt us." Tanguma is a specialist for students in second- to fifth-grade who need extra instruction in reading and math in the Bay City Independent School District.

Drescher said draft budgets didn't restore the cuts. "But there's still time before the final version is passed," she added.

Meanwhile, Sen. Dan Patrick, a Houston Republican who chairs the Senate Public Education Committee, appeared at a press conference in another corner of the Capitol with Texans Deserve Great Schools, a new group of policy experts and civic leaders. The coalition said it wants to apply other states' successful education policy to Texas.

It believes the state is adequately funding schools but should distribute that money better, said Caprice Young, vice president of education for the Houston-based Laura and John Arnold Foundation, which seeks to "minimize injustice in our society."

Texans Deserve Great Schools wants to lift the current cap of 215 charter schools licensed to operate statewide and believes public funding should go to cover charter facilities costs. It also wants to increase the number of Texas students who can earn school credit by taking courses online.

Additionally, the group is seeking to strengthen existing "parent trigger" laws so as to allow parents to petition to shut down a failing school after just two years. It further believes parents should have the option to send their children to the best public schools and not be "trapped by their zip code."

But the coalition stops short of endorsing voucher proposals that would let families use public money allotted for their children on private schools. "We're really about public schools," Young said.

Patrick has proposed expanding school vouchers, arguing that families who are wealthy enough buy homes in areas with quality school districts ? while their low-income counterparts are trapped in poor-performing districts.

"We must have empowerment and we must have flexibility," Patrick said Thursday.

Many of the teachers at the Capitol said they oppose vouchers because private schools can turn away students deemed undesirable, meaning struggling kids will be stuck in public schools that will lose funding as their classmates bolt.

Vouchers supporters say they could increase teacher pay because there may be added demand for top educators. But Teresa Koehler, a 30-year teaching veteran in Clear Creek Independent School District, near League City, said "the key word there is 'may.'"

"In the past, what they say will happen has not happened," she said.

Source: http://news.yahoo.com/texas-teachers-foundations-converge-capitol-161735017.html

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Three people shot at Houston-area community college, police say ...

Three people on campus at Lone Star College were injured in what may have been an argument that escalated. Nearby schools went into lockdown as parents waited to pick up their kids. NBC's Janet Shamlian reports.

By Jeff Black, Staff Writer, NBC News

Three people were wounded Tuesday afternoon when gunfire erupted at a Houston-area community college, law enforcement officials said.

Authorities confirmed at a news conference ?that two "persons of interest" were involved and wounded in an altercation at the North Harris campus of Lone Star College. A maintenance worker at the college was also shot in the leg during the crossfire, said Maj. Armando Tello, acting sheriff for the Harris County Sheriff's Office. School officials say the worker, in his mid-50s, was in stable condition.

Police later said Carlton Berry, 22. was charged with aggravated assault. He remained in the hospital early Wednesday, Harris County Sheriff's Office Director of Public Affairs Alan Bernstein told NBC News.

Police did not identify the second "person of interest."

Police said a fourth person, a female with a student ID, was transported from the scene to the hospital, for an unspecified "medical condition."

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The shooting happened outside in a courtyard between an academic building and a library, Richard Carpenter with the Lone Star College System said. Police were dispatched at 12:51 p.m. CT and were on the scene within two minutes, according to Tello.?Police confirmed a handgun was involved, but could not provide more information because the incident?remains?under investigation.

Several federal officials have said the incident was gang-related, but the exact nature of the relationship remained unclear.

Authorities say the shooting at a Texas community college was the result of an altercation between two people.

The school said on Twitter that the shooting occurred at about 12:31 p.m. Carpenter said the campus will reopen Wednesday.

Live aerial video taken from NBC station KPRC-TV?showed emergency crews moving two people on stretchers into ambulances.

Police officers in SWAT gear were shown on the video entering buildings on the campus and bringing out students.

A spokesperson for Ben Taub General Hospital confirmed to NBC News that two patients from the shooting had been treated there. A?Houston Northwest Medical Center spokesperson said it had two patients from the Lone Star College incident. Neither hospital would release more information about the patients.

Witness Amanda Vasquez told KPRC she was in English class with about 25 other students when she heard shots fired, she thought in the hallway. She said she got under her desk, while other students ran out of the classroom.?

"We closed the door and we put the table against the door," Vasquez said. "And we were hiding and I was just trying to call my mom to let her know I was OK."

Police came in after about 30 minutes and said they could come out, she said.

Jed Young, a spokesman for the college system, told The Associated Press that a "shelter-in-place order" was issued at the college due to reports of a shooter on campus.?Students, faculty and staff were advised by the college website to take immediate shelter where they were. The school later said it was on lockdown.?

Lone Star College is a community college system based in the Houston region and has six campuses associated with it.

Lone Star's North Harris campus is 20 miles north of Houston in unincorporated Harris County. The campus has roughly 19,000 students.

According to the Lone Star College website, weapons are not allowed on the campus. The school offers firearm safety courses through its Second Amendment Academy.

NBC's Pete Williams, Jonathan?Dienst, Vignesh Ramachandran and Matthew DeLuca contributed to this report.

Student Amanda Vasquez emotionally describes to KPRC the scene when a shooter on a Lone Star College campus in Texas opened fire. Vasquez says she heard "five or six" gunshots and saw one shooter.

Source: http://usnews.nbcnews.com/_news/2013/01/23/16645383-three-people-shot-at-houston-area-community-college-police-say

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China recovering from 'soft landing'

DAVOS, Switzerland (AP) ? The head of China's National Economic Research Institute says his country's economy is now recovering from its "soft landing" and that the big challenge in 2013 will be to prevent it overheating.

Fan Gang told a session on China's growth prospects at the World Economic Forum Wednesday that the world's second-largest economy should grow faster in 2013 than it did last year.

China posted growth of 7.8 percent last year, its weakest performance since the 1990s.

Fan said that in 2013 China could grow between 8 percent to 8.5 percent.

Source: http://news.yahoo.com/china-recovering-soft-landing-153216964--finance.html

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